Why Choose Simini

Broad Spectrum Activity


Simini Protect Gel  

Suspension Time Kill Testing (2 minutes)

Planktonic Efficacy 

Destroys Biofilms


Comparative In-Vitro Study of Simini-Protect Gel, Thermazene (silver treatment), Doxycycline  and Triclosan in the presence of biofilm.   Higher CFU (graph above) represents greater bacteria kill.

The "Best Line of DefenSE"

Saline: Current Standard



A rinsing agent used prior to surgical closure.

No anti-microbial activity.

No impact on biofilms or sessile bacteria.

Simini Protect Lavage vs. Saline


Murine Surgical Wound Model

Bacteria Removal from surgical wound - S. Aureus

(50 CFU Inoculum, 40-60 minute growth)

Texas Tech University

NEW Post-Surgical Protection

Prevents Bacterial Adhesions


Protect Wound When Most Susceptible to Infection


Laboratory In-Vitro Results

Testing confirmed bacteria are unable to migrate through or proliferate in the presence of Simini-Protect Gel.

Non-Antibiotic Product

No Known Resistance


Simini's physical mechanism of action is through bacterial cell lysis (breakdown of bacterial cell membranes).  There is no known resistance to this mechanism.

Aligned With Global Initiatives to Reduce Antibiotics


Doing our part in reducing antibiotic use and the growth of resistant infections.

How Simini Products Work

Learn About the Cutting Edge Science Behind These Surgical Products

Find out more